IN VIVO STUDY OF THE EFFECT OF A STRONTIUM-­‐RICH INJECTABLE SYSTEM ON BONE REGENERATION, USING A SHEEP MODEL

Bone has the capacity to regenerate as part of the repair process,being newly formed boné indistinguishable from the adjacente uninjured bone. However,there are cases in which boné regeneration is required in large quantity, beyond the normal potential for self-­‐healing, such as for lesions caused by trauma, infection, tumour resection or cases in which the regenerative process is compromised such as avascular necrosis and osteoporosis. Biomaterials such as alginate are very promising due to its ability to form hydrogels in situ under mild conditions in the presence of divalente cations. The combination with ceramic microspheres results in a mechanically improved injectable system, adequate for minimally invasive procedures. Moreover, the combination with chemical elements such as strontium, described as promoter of boné formation, inhibiting boné resorption provides ion Exchange between the implanted biomaterial and surrounding tissue, enhancing boné regeneration. Our goal is to study in na invivo sheep model, the effect of na injectable system composed of strontium doped hydroxyapatite microspheres, delivered in na alginate vehicle, crosslinked with strontium

Analysis of the genetic variability of peach palm (Bactris gasipaes) in the Yurimáguas region, Peru, using molecular RAPD markers

Molecular markers were used to verify the existence of one or more primitive peach palm landraces, including Pampa Hermosa, in the microregion near Yurimáguas, Peru. This region provides the highest amount of seeds for peach palm heart agribusinesses in Brazil. In this analysis, we used 120 peach palm plants (Bactris gasipaes var. gasipaes) from four river basins around Yurimáguas. We used six primers, generating 73 RAPD markers. The heterozygosity ranged from 0.29 to 0.31, with a mean of 0.32, and the percentage of polymorphism ranged from 80.8 to 86.6, with a mean of 90.4. The dendrogram, based on Jaccard Similarity, presented eight groups, but it did not present groups formed by the water basins. The average gene flow was high, ranging from 11.41 to 18.89, as expected for populations within a same landrace. The analysis of the genetic diversity in this set of plants showed a common genetic basis among the plants. Nei's Genetic Distances were low, varying between 0.012 and 0.027. This suggests that such populations are very similar to each other, and that there is only one landrace in the region. Therefore, we propose the existence of only one landrace in the Yurimáguas region and the name "Pampa Hermosa" should be adopted. © 2018 Cientifica. All rights reserved

MOONS: the Multi-Object Optical and Near-infrared Spectrograph for the VLT

Instrumentatio